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Nutrition in critical care
Pseudomonas infection and virulence
Serum specific indicators of severity of injury
Stroma free hemoglobin effect on cytokine production in acute and chronic illness

Primary Investigator:
Sepsis and Trauma.  (Phase IIB) - ICOS/Scirex

Severe Acute Pancreatitis (Phase II/III) - ICOS/Parexel 

The use of Oxandrolone in severe closed-head injuries.  (Phase IV) Investigator Initiated Protocol

Autograft Donor Sites in Burn Patients.  (Phase III) Ortec/The Phoenix

Acute Respiratory Distress Syndrome.  (Phase II) Suntory/PPD

S-100B protein in severe closed head injuries.  Investigator Initiated

Bradykinin & Cytokine Blood Levels in Burn/Trauma Patients.  Investigator

Treatment of Acute Lung Injury in the ICU.  (Phase II) Eli-Lilly/Omnicare

Treatment of Sepsis in the ICU.  (Phase III) ICOS/PPD

Early treatment of Sepsis in the ICU.  (Phase I) GlaxoSmithkline/PPD

Enterra Therapy: An emerging treatment option for drug-refractory gastroparesis

499E02-A Phase 2 Study of Recombinant Human Thrombin (rh Thrombin) Administered Using a Spray Applicator in Subjects Undergoing Autologous Skin Grafting Following Burn or Traumatic Skin Injury.

ACCESS: A Controlled Comparison of Eritoran Tetrasodium and Placebo in Patients with Severe Sepsis

A Phase III, Multi-center, Randomized, Evaluation Committee-blinded Study to Assess the Efficacy of Topical Administration of Omiganan 1.0% Gel in Preventing Local Catheter Site Infections and Catheter Colonization in Patients undergoing Central Venous Catheterization.

A Study To Evaluate The Safety And Efficacy Of Fibrin Sealant With 4IU/ML Thrombin Vapor Heated, Solvent/Detergent Treated (FS 4IU VH S/D) To Adhere Tissues And Improve Wound Healing

Analyzing the antibiotic resistance profile of bacterial isolates obtained from severely burned patients.

Burn Treatment Outcomes: A retrospective study for different protocols.

Relationship of Pseudomonas Aeruginosa virulence factors to clinical outcome of wound infection.

Functional outcome of 80 and 90 year old burn patients.

Trauma Team Activation from the Field

Radiology-Trauma Study

Paul Glat, Lisa Quirk, Scott Hultman, Jennifer Kesey, Arpana Jain, John Griswold, et.al.  Establishing Consensus of Best Practice for CEA Use in Treatment of Severe Burns: A US Burn Provider Delphi Study.  J Burn Care Res. 2024 Mar 19:irae050.
 doi: 10.1093/jbcr/irae050. Online ahead of print.

Habib Abla, Vivie Tran, Alan Pang, Stephanie Stroever, Chip Shaw, Sharmila Dissanaike, John Griswold. Assessing resuscitation in burn patients with varying degrees of liver disease.  Burns Volume 50, Issue 4, May 2024, Pages 991-996

Arden Perabo, Kathryn Keeney, Alan W Pang, Deepak Bharadia, John Griswold.  Lidocaine and Ketamine as Sedation for Burn Wound Care in a Pediatric Patient: A Case Report.  Journal of Acute Care Surgery 2024;14(1):34-36.  March 31, 2024.

Alan Pang, Jad Zeitouni, Ferris Zeitouni, Jennifer Kesey, John Griswold,
A modern-day research model for large academic institutions: A fellow-based solution.  Surgery in Practice and Science.  Volume 14, September 2023, 100193.

Elizabeth Brown, Michael Dang, Alan Pang, Senja Collins, Abbye Dixon, Deepak Bharadia, John Griswold.  Serial casting for the improvement of joint contracture after burn injury, a case report.  Burns Open, Volume 7, Issue 3, July 2023,
Pages 94-98.

J. Christian Bruce, Anna M. McGregor, Hector Garcia, Kiana Banafshay, Emily Brumfield, Alan Pang, Deepak Bharadia, John Griswold.  Charge capture in the BICU: Increasing revenue by improving documentation behaviors.  Burns,
Volume 49, Issue 4, June 2023, Pages 775-782.

Amanda Baty, Timothy I Matis, John Griswold. A simulation study on the association of HRO communication patterns and surgical team performance. International Journal for Quality in Health Care, Volume 34, Issue 2, 2022, mzac028,  15 April 2022.

Elmassry M, Mudaliar N, Colmer-Hamood J, San Francisco M, Griswold J, Dissanaike S, Hamood A. New markers for sepsis cause by Pseudomonas aeruginosa during burn infection Metabolomics 2020; 16 (3) :40.

Fleming D, Jiang D, Opoku K, Alhaj-Saleh A, Larumbe E, Kesey J, Griswold J, Dissanaike S. Prophylactic Probiotics in Burn Patients: Risk versus Reward Journal of Burn Care & Research 2019; 40 (6) :953-960.

Zhou Y, Zhang Y, Johnson A, Venable A, Griswold J, Pappas D. Detection of Culture-Positive and Culture-Negative Sepsis in Clinical Blood Samples using a Microfluidic Assay for CD64 and CD69 Cell Capture Analytica Chimica Acta 2019; 1062 :110-117.

Elmassry M, Mudaliar N, Kottapalli K, Dissanaike S, Griswold J, Francisco M, Colmer-Hamood J, Hamood A. Pseudomonas aeruginosa alters its transcriptome related to carbon metabolism and virulence as a possible survival strategy in blood from trauma patients mSystems 2019; 4 (4) :eCollection.

Zhou Y, Zhang Y, Johnson A, Venable A, Griswold J, Pappas D. Combined CD25, CD64, and CD69 biomarker panel for flow cytometry diagnosis of sepsis Talanta 2019; 191 :216-221.

Puckett Y, Zhang K, Blasingame J, Lorenzana J, Parameswaran S, Brooks SE, Baronia BC, Griswold J. 2018 July 03. Safest Time to Resume Oral Anticoagulation in Patients with Traumatic Brain Injury. Cureus 10(7): e2920. DOI 10.7759/cureus.2920

Zhang Y, Zhou Y, Li W, Lyons V, Johnson A, Venable A, Griswold J, Pappas D. A Multi-Parameter Affinity Microchip for Early Sepsis Diagnosis Based on CD64 and CD69 Expression and Cell Capture Analytical Chemistry 2018; 90 (12) :7204-7211.

Kim HG, Kesey, JE, Griswold JA.   Giant Anorectal Condyloma Acuminatum of Buschke-Lowenstein Presents Difficult Management Decisions.  Journal of Surgical Case Reports.  2018; 4, 1-4

Holmes JH 4th, Molnar JA, Carter JE, Hwang J, Cairns BA, King BT, Smith DJ, Cruse CW, Foster KN, Peck MD, Sood R, Feldman MJ, Jordan MH, Mozingo DW, Greenhalgh DG, Palmieri TL, Griswold JA, Dissanaike S, Hickerson WL.  A Comparative Study of the ReCell® Device and Autologous Spit-thickness Meshed Skin Graft in the Treatment of Acute Burn Injuries.  J Burn Care Res. 2018 May 24. doi: 10.1093/jbcr/iry029. [Epub ahead of print]

Davis CH, Kao LS, Fleming JB, Aloia TA; Texas Alliance for Surgical Quality Collaborative. Multi-Institution Analysis of Infection Control Practices Identifies the Subset Associated with Best Surgical Site Infection Performance: A Texas Alliance for Surgical Quality Collaborative Project. J Am Coll Surg. 2017 Aug 16. pii: S1072-7515(17)31665-4. doi: 10.1016/j.jamcollsurg.2017.07.1054.

Dzvova N, Colmer-Hamood JA, Griswold JA, Hamood AN. Heparinase Is Essential for Pseudomonas aeruginosa Virulence during Thermal Injury and Infection.  Infect Immun. 2017 Dec 19;86(1). pii: e00755-17. doi: 10.1128/IAI.00755-17. Print 2018 Jan

Dzvova N, Colmer-Hamood JA, Griswold JA, Hamood AN Isolation and characterization of HepP: a virulence-related Pseudomonas aeruginosa heparinase.  BMC Microbiol. 2017   Dec 16;17(1):233. doi: 10.1186/s12866-017-1141-0.

Zhang Y, Li W, Zhou Y, Johnson A, Venable A, Hassan A, Griswold J, Pappas D Detection of sepsis in patient blood samples using CD64 expression in a microfluidic cell separation device.  Analyst. 2017 Dec 18;143(1):241-249. doi: 10.1039/c7an01471f.

Kruczek C, Kottapalli KR, Dissanaike S, Dzvova N, Griswold JA, Colmer-Hamood JA, Hamood AN: Major transcriptome changes accompany the growth of Pseudomonas aeruginosa in blood from patients with severe thermal injuries. PLoS One.  11 (3): e0149229. doi: 10.1371/journal. pone.0149229.  Epub 2016 Mar 2

McKee D, Eliasson S, Griswold J: Case Report: Congenital Ulnar Drift in a Surgeon.  Case Reports in Orthopedics.  Vol 2015, Article 135350, 2015

Trivedi U, Parameswaran S, Armstrong A, Burgueno-Vega D, Griswold J, Dissanaike S, Rumbaugh K: Prevalence of Multiple Antibiotic Resistant infections in Diabetic versus Nondiabetic Wounds.  Journal of Pathogens. 2014:173053. PMID: 25054067, 2014

Dissanaike S, Abdul-Hamed S, Griswold JA: Variations in Perfusion Over Time as Measured by Portable ICG Fluorescence Indicates Depth of Burn: A Case Series.  Journal of Burn Care & Research.  2 (4): 201-205, 2014

Watters C, Deleon K, Trivedi U, Griswold JA, Lyte M, Hampel KJ, Wargo MJ, Rumbaugh KP: Pseudomonas aeruginosa biofilms perturb wound resolution and antibiotic tolerance in diabetic mice.  Medical Microbiology and Immunology.   202: 131-141, 2013 

Craig C, Klein M, Griswold J, Gaitonde K, McGill T, Halldorsson A: Using Cognitive Task Analysis to Identify Critical Decision in the Laparoscopic Environment.  Journal of Human Factors.  54 (6): 1025-39, 2012

Simoni J, Simoni G, Moeller J, Feola M, Griswold JA, Wesson D: ATP-Adenosine-Glutathione Cross-Linked Hemoglobin as Erythropoiesis-Stimulating Agent (ESA). Journal of Artificial Organs.  36 (2): 139-150, 2012

Griswold J: Why Diabetic Wounds Do Not Heal.  Texas Heart Institute Journal.  39 (6): 860-861, 2012

 

Schmitz B, Griswold JA: “Airway Management in Burn Patients”,  Airway Management.  Benumof & Hagberg 3rd edition.  2013, 44: pp 902-909

Lie DYC, Ichapurapu R, Jain S, Lopez J, Banister RE, Nguyen T, Griswold J: “A Novel Non-Contact Biosensor System for Continuous Monitoring of Vital-Signs and Handwashing Compliance”, In: Telemedicine, ISBN 978-953-307-1408-6, 2012, 9: pp 211-238

Illner H, Barber AE, Griswold JA, Hsia WG:  Emerging Therapeutic Targets - Volume One, 1997, editors: R Anand, P Smith, P Warne.  Ashley Publications Ltd, 1997, pp 257-261

Griswold JA: "Burns: Physical and Chemical Injuries", Conn's Current Therapy. editor: Rakel RE.  W.B. Saunders Co., 1996, pp 1127-1131

Mitchell M, Griswold J: "Management of Multiple Trauma." In: General Surgery. editors: Ritchie WP, Steele G, Dean RH. Philadelphia. J.B. Lippincott, 1995,pp.919-928.

Griswold JA:  "Sodium Concentrations and Burn Shock Resuscitation."  Problems in General Surgery.  J.B. Lippincott, 1994, 11:4, pp. 566-576

Griswold JA:  "White Blood Cell Response to Burn Injury", Seminars in Nephrology.  13: 4, pp. 409-415, 1993

Lindsey AK, Allen BC, Rhodes RS, Griswold JA: "Replacement of Infected Aortic Prosthetic Grafts with Vascularized Musculofascial Flaps", Modern Vascular Surgery. editor: Chang JB. Springer-Verlang, 1992, 5: pp 153-165

Griswold JA, Molnar JA: Toxic Epidermal Necrolysis. In: Martyn JA. ed. Acute Management of the Burned Patient. Philadelphia. W.B. Saunders Co., 1990, pp.128-137.

 

A Retrospective Study Analyzing Aesthesia Intubation Criteria in Burn Patients @
International Anesthesia Research Society (IARS) and Society of Critical Care Anesthesia (SOCCA) Research Conference, Seattle, WA, May 18-20, 2024

Sara Syed Ahmend B.S., Emily Brumfield B.S., Sulaiman Karim B.S., Heba Alghoul M.D., Theophilus Pham M.D., Alan Pang, M.D., & John Griswold M.D. Antihistamines vs. Resuscitation Requirements and Rate of Complications in Burn Injuries: A Retrospective Study. American Association for the Surgery of Trauma, Poster Presentation, Sept 20-23, 2023. Accepted

Colton Shepherd B.S., Nathan Behrens B.S., Alexander Dorius M.B.A., Carson Bateman B.S., Alan Pang MD, John Griswold MD. Changes in Geographic Medicare Reimbursement for General Surgeons from 2012-2022. American College of Surgeons Clinical Congress, Quickshot Presentation, Oct 22-25, 2023. Accepted.

Liza Garcia, Emily Brumfield, Alan Pang, John Griswold. Retroperitoneal Perforation of Colon with Precipitating Secondary Necrotizing Soft-Tissue Infection After Colonoscopy: A Case Report. April 16-19, 2023 in Ojai Valley Inn, California (Mini Oral SWSC 2023 Annual Meeting)

Raghuram A, Pang AW, Zeitouni J, Jang W, Householder N, Griswold J, Ronaghan C. Biodegradable temporizing matrix and autologous skin cell suspension in necrotizing soft tissue infection: a case report. John A. Boswick M.D. Burn and Wound Healing Symposium, 2022.

Brown E, Koshy R, Credo R, Grossman H, Hardy K, Rizvi M, Alshaikhsalama M, Devega R, Bharadia D, Pang AW, Griswold J. Autologous keratinocyte suspension in conjunction with fibrin sealant for the treatment of partial thickness burns. John A. Boswick M.D. Burn and Wound Healing Symposium, 2022. Podium Presentation.

Pang AW, Pham T, Raghuram A, Zeitouni J, Aickareth G, Dang M, Bharadia D, Griswold J. Comparison of Amalgatome SD to standard dermatome for surgical excision of burns and skin graft harvesting. John A. Boswick M.D. Burn and Wound Healing Symposium, 2022.

Perabo, A, Robison, K, Pang, AW, Bharadia, D, Griswold, J. “Lidocaine and Ketamine as Sedation for Burn Wound Care in a Pediatric Patient: a case report.” North Texas Chapter of American College of Surgeons Annual Meeting, Poster Presentation, 2022.

Zeitouni, J, Pang, AW, Bradshaw, E, Rizvi, M, Bharadia, D, Griswold, J. “Alkali injury with non-operative management in a pediatric patient: a case report.” North Texas Chapter of American College of Surgeons Annual Meeting, Poster Presentation, 2022.

Bruce, J, McGregor, A, Kesey, J, Pang, AW, Griswold, J. “Charge capture in the BICU: Increasing Revenue by Improving Documentation.” North Texas Chapter of American College of Surgeons Annual Meeting, Podium Presentation, 2022.

Koshy, R, Brown, E, Pang, AW, Bharadia, D, Griswold, J. “Postoperative Splinting vs free range of motion and effect on healing time of ReCell for partial thickness burns.” North Texas Chapter of American College of Surgeons Annual Meeting, Podium Presentation, 2022.

Dang, M, Brown, E, Huynh, J, McReynolds, S, Pang, AW, Caroom, C, Ronaghan, C. “Open Pelvic Fracture with Resultant Chronic Sinus Tract Secondary to Bone Fragment Sequestrum: A case study and literature review”. North Texas Chapter of American College of Surgeons Annual Meeting, Poster Presentation, 2022.

Bradshaw, E, Pang, AW, Bharadia, D. “Using Geography as a Predictive Factor of Outcomes in Burn Care Follow-up in Rural West Texas.” North Texas Chapter of American College of Surgeons Annual Meeting, Poster Presentation, 2022.

Abla, Habib, Pang, Alan, Batchinsky, Maria, Raghuram, Akshay, Bharadia, Deepak,
John A. Griswold, M.D.  “Synergistic Surgical Treatment Decreases Length of Stay in Burn ICU: A Case Series.” AcademyHealth Annual Research Meeting, Accepted for poster presentation, 2022.

John Griswold, M.D., Akshay Raghuram, BA “Serial Envenomation in A Snake Handler with Severe Coagulopathy: A Case Study”
SWSC 2022 Podium Presentation

Dan Stuart PhD, John Griswold MD, Cathy Lovett RN “Effectiveness of evidence-based medicine instruction in medical school clerkships
Jan 2022