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“Understanding what medications do to people, and what people do to medications.”

The Center seeks to improve the understanding of how medications work in real-world settings so that clinicians, patients, policy makers and health systems can make better decisions about healthcare.

Real-world evidence (RWE) is data collected from patients in their everyday lives, outside of clinical trials. RWE can be used to understand how medications work in real-world settings, including how well they are tolerated, how effective they are, and how they interact with other medications. The Center for Excellence in Real-world Evidence provides support for research and training, and is a leading resource for high-quality research on medication usage, risks, and effectiveness among large populations.

The Center leverages large datasets to generate knowledge on medications by using sophisticated analytic techniques to get the most accurate, precise, and timely estimates to improve public health. This evidence complements data and knowledge from randomized, controlled trials.