Pradeep Jangampalli, PhD

Research Assistant Professor

I received my Ph.D. in Bioinformatics from Sri Venkateswara University. In my Ph.D. findings, I undertook a challenging research problem on "Identification and characterization of potential drug targets in Brucella genomes." I identified few putative drug targets genes that are potential candidate for Brucella pathogenesis through computational studies like molecular modeling, molecular docking, molecular dynamic simulation studies, and pharmacophore in drug discovery.

Currently, I am working on a project for identification of potential drugs (small molecules) for Alzheimer's disease (AD) and other neuronal disorders. Small molecule therapeutics, neuronal interaction, molecular behavior, in vitro cells cultures and animal models tests are used for drug discovery and computational screening to find the best possible rational therapeutic small molecules for AD and other neurological disorders. I am looking at small molecules involvement of therapeutic protection with inhibition against neurodegeneration including the role of secretase and tau components, synaptic, biogenesis and mitochondrial dynamic proteins and genes role in the pathogenesis of AD including Tau and APP metabolism.

1. Jangampalli Adi Pradeepkiran, Arubala P Reddy, P. Hemachandra Reddy. A small molecule Hyperphosphorylated tau (p-tau) inhibitor probing for Possible Therapeutic development in Alzheimer Disease and Tauopathies. Presented SfN 2022, Washington, DC.

2. Pradeepkiran JA, Swapnarekha S, Gurunadham G, Narasimha Rao G and Bhaskar M. Insights of Rheumatoid Arthritis in humans 鈥� A Review. Global Summit on 鈥淓merging Science and Technologies: Impact on Environment and Human Health鈥�.Special Symposia on 鈥淐ancer Therapy, Environmental Toxicology鈥�. Dept of Biotechnology, Vikrama Simhapuri University, Nellore, 1st 鈥� 3rd August 2014.

3. Pradeepkiran JA and Bhaskar M Discovery of peptide- based inhibitors for the protein Deiminase type 4 (PAD4) by structure based virtual screening. Global Summit on 鈥淓merging Science and Technologies: Impact on Environment and Human Health鈥�. Special Symposia on 鈥淐ancer Therapy, Environmental Toxicology鈥�. Dept of Biotechnology, Vikrama Simhapuri University, Nellore, 1st 鈥� 3rd August, 2014.

4. J.A. Pradeepkiran, Sudheer Aluru, S Mannur Ismail, M. Bhaskar. Amelioration effect of probiotics on afb1 induced homological alterations in fresh water fish Cyprinus carpio. (L). National Seminar on 鈥淐onservation of Animal Biodiversity and Environmental Monitoring鈥� Dept of Zoology, P.G. Centre, Vikrama Simhapuri University, Kavali during 11th to 12th March, 2014.

5. J.A. Pradeepkiran, P. Hemachandra Reddy. Pharmacophore based screening and molecular docking probing the novel inhibitors against BACE1 of Alzheimer鈥檚 disease. Center of Excellence for Translational Neuroscience and Therapeutics (CTNT) Symposium 2017, Texas Tech University Health Sciences Center Lubbock, Texas 79430.

6. Pradeepkiran JA and P. Hemachandra Reddy. Protective Effects of BACE1 Inhibitory Ligand Against Amyloid Beta-Induced Synaptic and Mitochondrial Toxicities in Alzheimer鈥檚 disease. 2018, Regional Healthy Aging and Dementia Research Symposium. Texas Tech University Health Sciences Center (甜瓜视频) Lubbock, Texas 79430.

7. Pradeepkiran JA and P. Hemachandra Reddy. Whole transcriptome analysis dissecting the differential gene expression profiles of Alzheimer鈥檚 disease samples with next generation sequencing method - RNA-Seq. 2018, Regional Healthy Aging And Dementia Research Symposium. Texas Tech University Health Sciences Center (甜瓜视频) Lubbock, Texas 79430.

8. Pradeepkiran JA and P. Hemachandra Reddy. Structure Based Design and Molecular Docking Studies for Phosphorylated Tau Inhibitors in Alzheimer 鈥檚 disease. 2018, Regional Healthy Aging and Dementia Research Symposium. Texas Tech University Health Sciences Center (甜瓜视频) Lubbock, Texas 79430.

9. Kranthi Kumar K, Pradeepkiran J.A., Bhaskar M. Molecular Modeling, Dynamic Simulations And Docking Studies Of Tyrosine Kinase Domain A Potential Drug Target In Cancer. PEBHT-2013. Dept of Zoology, SVU, Tirupati. 17th 鈥� 19th December 2013.

10. G.C. Haritha, CH. Anil Krishna, J.A. Pradeep Kiran, G. Sivani and M. Bhaskar. Impact of acid rains on fish culture 鈥� A Review. ETACO, SVU, 30-31 Aug,2012.

11. Y. Nanda Kumar, J.A. Pradeep Kiran, P.V.G.K.Sarma and M. Bhaskar. Structure Based Virtual Screening of Novel Inhibitors Against D-Alanine-D-Alanine Ligase, a Therapeutic Target of Salmonella typhi. National Seminar on 鈥楨merging Trends in Biotechnology: Challenges and Opportunities鈥� Mar-2012, Dravidian University, Kuppam, AP, India.

12. K. Subba Rao, M. Mohana Radhika, J.A. Pradeep kiran, G. Narasimhulu, G. Gurunadham, M. Bhaskar. Effect of Cadmium induced Metabolic alterations in Heart and Muscle of Female Rabbit. IEHTA, VSU, 15th -17th July, 2012.

1. Jangampalli Adi Pradeepkiran, Javaria Baig, Ashley Seman, P. Hemachandra Reddy. Mitochondria in Aging and Alzheimer 鈥檚 disease: Focus on Mitophagy鈥擳he Neuroscientist 2023, Jan 3:10738584221139761. https://doi.org/10.1177/10738584221139761

2. Jangampalli Adi Pradeepkiran, Manne Munikumar, Arubala P Reddy, P Hemachandra Reddy. Protective effects of a small molecule inhibitor ligand against hyperphosphorylated tau-induced mitochondrial and synaptic toxicities in Alzheimer disease. Human Molecular Genetics, (2022) 31, (2), 244鈥�261. https://doi.org/10.1093/hmg/ddab244

3. Jangampalli Adi Pradeepkiran and P. Hemachandra Reddy. Mitophagy events in mitochondrial fusion and fission machinery in Alzheimer鈥檚 disease. Ageing Research Reviews, (2020), 64, 101191. https://doi.org/10.1016/j.arr.2020.101191

4. Jangampalli Adi Pradeepkiran, Hemachandra reddy. Protective Effects of BACE1 Inhibitory Ligand Molecules Against Amyloid Beta-Induced Synaptic and Mitochondrial Toxicities in Alzheimer鈥檚 disease. Human Molecular Genetics, (2020) 29, (1), 49鈥�69. https://doi.org/10.1093/hmg/ddz227

5. Jangampalli Adi Pradeepkiran, Hemachandra reddy. Structure based design and molecular docking studies for phosphorylated tau inhibitors in Alzheimer鈥檚 disease. Cells (2019), 8(3), 260; https://doi.org/10.3390/cells8030260

6. Jangampalli Adi Pradeepkiran, Arubala P Reddy, P Hemachandra Reddy. Pharmacophore-based models for therapeutic drugs against phosphorylated tau in Alzheimer鈥檚 disease. Drug Discovery Today, (2018), 24, (2), 616-623. https://doi.org/10.1016/j.drudis.2018.11.005

7. Jangampalli Adi Pradeepkiran, Ashly Hindle, Sudhir Kshirsagara P. Hemachandra Reddy. Are mitophagy enhancers therapeutic targets for Alzheimer鈥檚 disease? Biomedicine & Pharmacotherapy(2022), 149, 112918. https://doi.org/10.1016/j.biopha.2022.112918

8. Jangampalli Adi Pradeepkiran, Hemachandra reddy. Phosphorylated tau targeted small-molecule PROTACs for the treatment of Alzheimer's disease and Tauopathies. BBA Molecular Basis of Disease. 2021, 1867(8):166162. https://doi.org/10.1016/j.bbadis.2021.166162

9. Javaria Baig, Jangampalli Adi Pradeepkiran and P. Hemachandra Reddy. Methods to Study the Mitochondria - qRT-PCR, Western Blotting, Immunofluorescence, Electron Microscopy, 鈥淔luorescence鈥�, and Seahorse 鈥� techniques used to study the effects of age-related diseases like Alzheimer鈥檚. Current Protocols, 3, e631. https://doi: 10.1002/cpz1.631

10. Muthyam Sowjanya, Bhagavathula Venkata Sandeep, Kaduru Venkaiah, Vijaya R. Dirisala, Malapati Hanuma Reddy, Jangampalli Adi Pradeepkiran, and Sri Bhashyam Sainath. Purification, Structural Elucidation, and Anticancerous Properties of a Novel Flavonoid from Flowers of Leucas indica. Processes 2022, 10(11), 2341; https://doi.org/10.3390/pr10112341

11. Pulak R.Manna, Arubala P. Reddy, Jangampalli Adi Pradeepkiran, SudhirKshirsagar, P. Hemachandra Reddy. Regulation of retinoid mediated StAR transcription and steroidogenesis in hippocampal neuronal cells: Implications for StAR in protecting Alzheimer's disease. BBA Molecular Basis of Disease. 2022:166596. https://doi.org/10.1016/j.bbadis.2022.166596

12. Murali Vijayan, Rainier Vladlen Alvir, Razelle Vladlen Alvir, Lloyd E Bunquin, Jangampalli Adi Pradeepkiran, P Hemachandra Reddy. A partial reduction of VDAC1 enhances mitophagy, autophagy, synaptic activities in a transgenic Tau mouse model. Aging Cell. 2022:e13663. https://doi.org/10.1111/acel.13663

13. Ashly Hindle, Sharda P Singh, Jangampalli Adi Pradeepkiran, Chhanda Bose, Murali Vijayan, Sudhir Kshirsagar, Neha A Sawant, P Hemachandra Reddy. Rlip76: An Unexplored Player in Neurodegeneration and Alzheimer鈥檚 Disease?. Int. J. Mol. Sci. 2022, 23(11), 6098; https://doi.org/10.3390/ijms23116098

14. Kaduru Venkaiah, Thathapudi Daveedu, Papisetty Prathima, Ramanadhapuram Pavani, Sadepalli Sukeerthi, Malapati Hanuma Reddy, Jangampalli Adi Pradeepkiran, Sri Bhashyam Sainath. Immobilization stress exacerbates arsenic-induced reprotoxic effects in adult rats. Toxicology Research, tfac022, https://doi.org/10.1093/toxres/tfac022

15. Mahesh. S, Boya Palajonnala Narasaiah, Balaji GL, Jangampalli Adi Pradeepkiran, Harihara Padhy. Sunflower-Assisted Bio-Derived ZnO-NPs as an Efficient Nanocatalyst for the Synthesis of Novel Quinazolines with Highly Antioxidant Activities. Antioxidants 2022, 11(4), 688; https://doi.org/10.3390/antiox11040688

16. Sudhir Kshirsagar, Rainier Vladlen Alvir, Ashly Hindle, Subodh Kumar, Murali Vijayan, Jangampalli Adi Pradeepkiran, Arubala P Reddy, Bhagavathi Ramasubramanian, P Hemachandra Reddy. Early Cellular, Molecular, Morphological and Behavioral Changes in the Humanized Amyloid-Beta-Knock-In Mouse Model of Late-Onset Alzheimer鈥檚 Disease. Cells 2022, 11(4), 733; https://doi.org/10.3390/cells11040733

17. Ramesh Kandimalla, Maria Manczak, Jangampalli Adi Pradeepkiran, Hallie Morton, P Hemachandra Reddy. A partial reduction of Drp1 improves cognitive behavior and enhances mitophagy, autophagy and dendritic spines in a transgenic tau mouse model of Alzheimer disease. Human Molecular Genetics. ddab360, https://doi.org/10.1093/hmg/ddab360

18. Subodh Kumar, Hallie Morton, Neha Sawant, Erika Orlov, Lloyd E Bunquin, Jangampalli Adi Pradeepkiran, Razelle Alvir, P Hemachandra Reddy. MicroRNA-455-3p improves synaptic, cognitive functions and extends lifespan: Relevance to Alzheimer's disease. Redox Biology. 2021 (48), 102182. https://doi.org/10.1016/j.redox.2021.102182

19. Morton H, Kshirsagar S, Orlov E, Buquin LE, Sawant N, Boleng L, George M, Basu T, Ramasubramanian B, Pradeepkiran JA, Kumar S, Vijayan M, Reddy AP, Reddy PH. Defective mitophagy and synaptic degeneration in Alzheimer's disease: Focus on aging, mitochondria and synapse. Free Radic Biol Med. 2021 Jul 8:S0891-5849(21)00412-3. doi: 10.1016/j.freeradbiomed.2021.07.013

20. Venkataramaiah C, Priya BL, Payani S, Pradeepkiran JA. Pharmacological Potentiality of Bioactive Flavonoid against Ketamine Induced Cell Death of PC 12 Cell Lines: An In Vitro Study. Antioxidants. (2021), 10(6):934. https://doi.org/10.3390/antiox10060934

21. P. Hemachandra Reddy, Xiangling Yin, Maria Manczak, Subodh Kumar, Pradeepkiran Jangampalli Adi, Murali Vijayan, Arubala P Reddy. Mutant APP and Amyloid beta-induced defective autophagy, mitophagy, mitochondrial structural and functional changes and synaptic damage in hippocampal neurons from Alzheimer鈥檚 disease. Human Molecular Genetics, (2018) 27, (14), 2502鈥�2516. https://doi.org/10.1093/hmg/ddy154

22. Chintha Venkataramaiah, Sholapuri Payani, Bandila Lakshmi Priya, Jangampalli Adi Pradeepkiran. Therapeutic potentiality of a new flavonoid against ketamine induced glutamatergic dysregulation in schizophrenia: In vivo and in silico approach. Biomedicine & Pharmacotherapy, (2021) 138, 111453. https://doi.org/10.1016/j.biopha.2021.111453

23. Jasvinder Singh Bhatti, Kavya Tamara, Ramesh Kandimall, Maria Manczak, Xiangling Yin, Bhagavathi Ramasubramanian, Neha Sawant, Jangampalli Adi Pradeepkiran, Murali Vijayane, Subodh Kumar, P. Hemachandra Reddy. Protective effects of a mitochondria-targeted small peptide SS31 against hyperglycemia-induced mitochondrial abnormalities in the liver tissues of diabetic mice, Tallyho/JngJ mice. Mitochondrion, (2021), https://doi.org/10.1016/j.mito.2021.02.007

24. Payani Sholapuri, Venkataramaiah Chintha, Bhaskar Matcha, Jangampalli Adi Pradeepkiran. Beneficial effects of polyherbal formulation (Bronco-T) on formaldehyde-induced lung toxicity in male Wistar rats. Toxicology Research, (2020), 9(6), 798鈥�807. https://doi.org/10.1093/toxres/tfaa083

25. Pradeepkiran Jangampalli Adi, Venkata Subbaiah Nandyala, Matcha Bhaskar. Trigonella foenum-graecum seeds extract plays a beneficial role on brain antioxidant and oxidative status in alloxan-induced Wistar rats. Food Quality and Safety, (2020), 4 (2), 83鈥�89. https://doi.org/10.1093/fqsafe/fyaa015

26. T. Sri Ranjani, Gopi Krishna Pitchika, K. Yedukondalu, Y. Gunavathi, T. Daveedu, S.B. Sainath, G.H. Philip and Jangampalli Adi Pradeepkiran. Phenotypic and transcriptomic changes in zebrafish (Danio rerio) embryos/larvae following cypermethrin exposure. Chemosphere, (2020), 249, 126148. https://doi.org/10.1016/j.chemosphere.2020.126148

27. Madhu Sudhana Saddala, Jangampalli Adi Pradeepkiran Synthesis, biological evaluation and molecular docking studies of novel dihydropyridine analogs as potent antioxidants. Current Topics in Medicinal Chemistry, (2019), 19, 1-11.

DOI: 10.2174/1568026619666191105100959

28. Jangampalli Adi Pradeepkiran, Insights of rheumatoid arthritis risk factors and associations. Journal of Translational Autoimmunity, (2019) 2, 100012. https://doi.org/10.1016/j.jtauto.2019.100012

29. Praveen Chakravarthi Veeraragavulu, Nanda Kumar Yellapu, Sireesha Yerrathota,

Pradeepkiran Jangampalli Adi, and Bhaskar Matcha, Three Novel Mutations I65S, R66S, and G86R Divulge Significant Conformational Variations in the PTB Domain of the IRS1 Gene. ACS Omega, (2019), 4, (1): 2217-2224. https://doi.org/10.1021/acsomega.8b01712

30. P. Hemachandra Reddy, Maria Manczak, Xiangling Yin, Mary Catherine Grady, Andrew Mitchell, Sahil Tonk, Chandra Sekhar Kuruva, Jasvinder Singh Bhatti, Ramesh Kandimalla, Murali Vijayan, Subodh Kumar, Rui Wang, Jangampalli Adi Pradeepkiran, Gilbert Ogunmokun, Kavya Thamarai, Kandi Quesada, Annette Boles, Arubala P. Reddy. Protective Effects of Indian Spice Curcumin Against Amyloid-尾 in Alzheimer鈥檚 Disease. Journal of Alzheimer's disease. (2018) 61(3):843-866.

DOI: 10.3233/JAD-170512

31. P. Hemachandra Reddy, Russell H. Swerdlow, John Culberson, David Kang, Tedd L. Mitchell,Quentin Smith, Sanoj Suneja, Marcia G. Ory, Subodh Kumar, Murali Vijayan, Ahmed Morsy, Gabriela Arandia, J. Josh Lawrence, Elizabeth George, Darryll Oliver, Jangampalli Adi Pradeepkiran, Xiangling Yin, Arubala P. Reddy, Maria Manczak, Pelin Cengiz1, Vardan T. Karamyan, Ramesh Kandimalla, Chandra Sekhar Kuruva, Joshua Willms1, Bhagavathi Ramasubramanian, Neha Sawant, Divya Burugu, Annette N. Boles, Veronica Lopez, Rocio Carrasco, Cordelia Aguirre, Susan Thompson, Joan Blackmon, Clay Ament, Rui Wang, Emily R. Stephens, Brittney Hoang, Kevin Bass, Paul C. Trippier, Christopher Hornback, Pratibha Kottapalli, Kameswara Rao Kottapalli, Center Biotechnology and Genetics Core Facility,Salvatore Oddo. Current Status of Healthy Aging and Dementia Research: A Symposium Summary. Journal of Alzheimer鈥檚 disease xx (2019) 1鈥�25. DOI 10.3233/JAD-190252.

32. Madhu Sudhana Saddala, Pradeepkiran Jangampalli Adi. Discovery of small molecules through pharmacophore modeling, docking and molecular dynamics simulation against Plasmodium vivax Vivapain-3 (VP-3). Heliyon, (2018) 4 (5) https://doi.org/10.1016/j.heliyon.2018.e00612

33. Somesula Swapna Rekha, Jangampalli Adi Pradeepkiran, Matcha Bhaskar. Bioflavonoid hesperidin possesses the anti-hyperglycemic and hypolipidemic property in STZ induced diabetic myocardial ischemia (DMI) in male Wister rats. Journal of Nutrition & Intermediary Metabolism, (2019). https://doi.org/10.1016/j.jnim.2018.12.004

34. Jangampalli Adi Pradeepkiran. Aquaculture role in global food security with nutritional value: a review. Translational Animal Science, (2019) 3, 2. https://doi.org/10.1093/tas/txz012

35. Jangampalli Adi Pradeepkiran, Sainath S.B., kranthi kumar konidala, Matcha Bhaskar. Complete genome-wide screening and subtractive genomic approach revealed new virulence factors, potential drug targets against bio-war pathogen Brucella melitensis 16M. Drug Design, Development and Therapy (2015) 9, 1-16. doi:10.2147/DDDT.S76948

36. Pradeepkiran Jangampalli Adi and Bhaskar Matcha. Analysis of aflatoxin B1 in contaminated feed, media, and serum samples of Cyprinus carpio L. by high-performance liquid chromatography. Food Quality and Safety, (2018) 2, (4): 199鈥�204. https://doi.org/10.1093/fqsafe/fyy013.

37. Pradeepkiran Jangampalli Adi, Jagadish R. Naidu, Bhaskar Matcha. Multiplex quantification of Escherichia coli, Salmonella typhi and Vibrio cholera with three DNA targets in single reaction assay. Microbial Pathogenesis. (2017) https://doi.org/10.1016/j.micpath.2017.06.010.

38. Nanda Kumar Yellapu, Kalpana Kandlapalli, Pradeepkiran Jangampalli Adi. Conformational transition pathway of R308K mutant glucokinase in presence of the glucokinase activator YNKGKA4. FEBS Open Bio (2017) https://doi.org/10.1002/2211-5463.12255

39. Jangampalli Adi Pradeepkiran, Konidala Kranthi Kumar, Y. Nanda Kumar, Matcha Bhaskar. Modeling, molecular dynamics, and docking assessment of transcription factor rho: a potential drug target in Brucella melitensis 16M. Drug Design, Development and Therapy, (2015) (9) 1-16. doi:10.2147/DDDT.S77020.

40. Jangampalli Adi Pradeepkiran, Sri Bhashyam Sainath, Konidala Kranthi Kumar, Kodali Vidya Prabhakar, Lokanada Balasubramanyam, Matcha Bhaskar. CGMD: An integrated database of cancer genes and markers. Scientific Reports (2015), 5, 12035. http://dx.doi.org/10.1038/srep12035.

41. Madhu Sudaba Saddala, Ramesh Kandimalla, Pradeepkiran Jangampalli Adi, Sainath Sri Bhashyam, Usha Rani. Novel 1, 4-dihydropyridines for L-type calcium channel as antagonists for cadmium toxicity. Scientific Reports. (2017) https://doi.org/10.1038/srep45211

42. Jangampalli Adi Pradeepkiran, Burra Siva Prasad, Vatapatri Amardev Rajesh, Matcha

Bhaskar. Calcium, zinc and vitamin E ameliorate cadmium-induced renal oxidative damage in albino Wistar rats. Toxicology Reports 3 (2016) 591鈥�597. http://dx.doi.org/10.1016/j.toxrep.2016.07.005.

43. Jangampalli Adi Pradeepkiran, Nanda Kumar Yellapu, Bhaskar Matcha, Modeling, molecular docking, elucidated catalytic binding mode of acetyl-CoA malate synthase G in Brucella melitensis 16M. Biochemistry and Biophysics Reports 8 (2016) 192鈥�199. http://dx.doi.org/10.1016/j.bbrep.2016.08.020.

44. Madhu Sudhana Saddala, Pradeep Kiran Jangampalli Adi, Vengala Rao Patchava and Usha Rani A. Selenoergothionein as a Potential Inhibitor against Amyloid 尾-Protein (A尾): Docking and Molecular Dynamics Studies. International Journal of Biomedical Data Mining, 5: 120. (2016). doi:10.4172/2090-4924.1000120.

45. Pradeep Kiran Jangampalli Adi, P. Ramesh Babu, V. Praveen Chakravarthi, Matcha Bhaskar, Multiplex PCR assay for the simultaneous detection of C. perfringens, P. aeruginosa and K. pneumoniae, Pathogenesis 2, (2015); 21-26

doi: 10.1016/j.pathog.2015.09.001.

46. Pradeep Kiran Jangampalli Adi and Bhaskar Matcha. Environmental Acidification Impact on Fisheries by Changing Oxidative Markers of Liver and Intestine of Freshwater Fish Cyprinus Carpio. L. Poult Fish Wildl Sci (2016); 4:1. DOI:10.4172/2375-446X.1000146

47. Jangampalli Adi Pradeepkiran, Veeraraghavulu Praveen Chakravarthi, Yellapu Nanda Kumar, Somesula Swapna Rekha, Srinivasan Shanthi Kruti, Matcha Bhaskar. Comparison and correlation of Simple Sequence Repeats distribution in genomes of Brucella species. Bioinformation. (2011), 6, (5):179-82. DOI: 10.6026/97320630006179.

48. J.A. Pradeepkiran, A. Sudheer kumar, S. Mannur Ismail, E. Madhuri, M. Bhaskar: Amelioration effect of probiotics (Cheese) and prebiotic (Garlic) on aflatoxin B1 induced hematological alterations in fresh water fish Cyprinus carpio L. Online Journal of Animal and Feed Research. (2015), 5, (4): 117-124.

49. Ravi Naik Mude, Swapna Rekha Somesula, Pradeepkiran Jangampalli Adi, Bhaskar Matcha. Diabetic regulation through blood constituents' modulations on treatment with Aloe vera in alloxan induced diabetic rats. Digest Journal of Nanomaterials and Biostructures. (2012), 7, (2) 649 - 655.

50. Radha Madhavi Yeggnisetty Ramachandraiahgari, Swapna Rekha Somesula, Jangampalli Adi Pradeepkiran, Ismail Shaik Mannur, Madhuri Enamala, Bhaskar Matcha: Protective role of ethanolic extract of Aloe vera antioxidant properties on liver and kidney of streptozotocin-induced diabetic rats. Digest Journal of Nanomaterials and Biostructures (2010, 7, (1): 175-184.

51. V. Praveen Chakravarthi, Y. Nanda Kumar, K. Mahamanjunath, A. Rukmini, D. Bhavani, J. A. Pradeepkiran, T. Chiranjeevi, M. Ismail, J. Durga Prasad, M. Bhaskar: Analysis of polymorphism in Kir 6.2 gene in Type 2 diabetic patients. Asian Journal of Biomedical and Pharmaceutical Sciences. (2014), 4 (37), 15-20.

52. K. Subba Rao, J. A. Pradeepkiran, Praveen Chakravarthi Veeraraghavulu, M. Bhaskar: Effect of cadmium on antioxidant metabolic modulations in heart and muscle of female rabbits. International Journal of Pharmacy and Biological Sciences (2013); 3(1):409-415.

53. V. Praveen Chakravarthi, J. A. Pradeepkiran, M. Bhaskar: Cadmium toxicity - A health hazard and a serious environmental problem - An overview. International Journal of Pharmacy and Biological Sciences (2012); 2(4):235-246.

54. Y. Nanda Kumar, J.A. Pradeepkiran, P. Santhosh Kumar, S. Yeswanth, K. Kalpana, V. Koteswara Rao, P.V.G.K. Sarma, M. Bhaskar: Molecular Docking Assessment of Pyridone Derivatives as Glucokinase Activators. J Clin Sci Res. (2012), 1:163-73. doi.org/10.15380/2277-5706.JCSR.12.035.

55. Yellapu Nanda Kumar, Pasupuleti Santhosh Kumar, Gopal Sowjenya, Valasani Koteswara Rao, Sthanikam Yeswanth, Uppu Venkateswara Prasad, Jangampalli Adi Pradeepkiran, P.V.G.K. Sarma, Matcha Bhaskar: Comparison and correlation of binding mode of ATP in the kinase domains of Hexokinase family. Bioinformation (2012), 8, (12), 543-7. DOI: 10.6026/97320630008543.

CLICK THE LINK FOR COMPLE LIST OF PUBLICATIONS

Book (1)

1. I edited a book as a 鈥楤rucella Melitensis Identification and Characterization of Potential Drug Targets鈥�. (Elsevier Science and Academic Press), Jangampalli Adi Pradeepkiran, S.B. Sainath ISBN 978-0-323-85681-2 (2021). https://doi.org/10.1016/C2020-0-03079-3

Chapters (6)

1. Jangampalli Adi Pradeepkiran, M. Bhaskar, K.V.L. Shrikanya, P. Gopi Krishna, M. Hanuma Reddy, Ch Venkatrayulu and S.B. Sainath. Chapter 1. (2021). Introduction to brucellosis., Brucella Melitensis Identification and Characterization of Potential Drug Targets. (Academic Press). https://doi.org/10.1016/B978-0-323-85681-2.00007-0

2. Jangampalli Adi Pradeepkiran, S.B. Sainath, Manne Munikumar and Kanipakam Hema. Chapter 2. (2021). Identification and characterization of vaccine targets for Brucella melitensis through in silico approaches. (Academic Press). https://doi.org/10.1016/B978-0-323-85681-2.00004-5

3. Jangampalli Adi Pradeepkiran, S.B. Sainath, Praveen K. Balne and M. Bhaskar. Chapter 3 (2021). Computational modeling and evaluation of best potential drug targets through comparative modeling. (Academic Press). https://doi.org/10.1016/B978-0-323-85681-2.00001-X

4. Jangampalli Adi Pradeepkiran, Manne Munikumar, Kanipakam Hema, Pradeep Natarajan and S.B. Sainath. Chapter 4 (2021). Molecular docking and dynamics simulations of novel drug targets. Identification and Characterization of Potential Drug Targets. (Academic Press). https://doi.org/10.1016/B978-0-323-85681-2.00005-7

5. Jangampalli Adi Pradeepkiran, S.B. Sainath and K.V.L. Shrikanya. Chapter 5 - In silico validation and ADMET analysis for the best lead molecules. (Academic Press) https://doi.org/10.1016/B978-0-323-85681-2.00008-2

6. Jangampalli Adi Pradeepkiran, S.B. Sainath. Chapter 6 - Summary and conclusions. https://doi.org/10.1016/B978-0-323-85681-2.00002-1.

UGC BSR Scholarship: The Research Meritorious Fellowship in Sciences for the outstanding PhD candidates.

路 Junior Research Fellow: Department of Biotechnology DBT.

路 Senior Research Fellow: Department of Biotechnology DBT.

路 2018- *Best poster award received at Regional Healthy Aging and Dementia Research Symposium at Lubbock, Texas, USA.